{"id":5599,"date":"2024-09-22T16:19:09","date_gmt":"2024-09-22T13:19:09","guid":{"rendered":"https:\/\/hospitalitymedservice.com\/?post_type=diseases&p=5599"},"modified":"2025-08-08T10:35:30","modified_gmt":"2025-08-08T07:35:30","slug":"wilms-tumor","status":"publish","type":"diseases","link":"https:\/\/hospitalitymedservice.com\/en\/diseases\/wilms-tumor\/","title":{"rendered":"Nephroblastoma (Wilms Tumor)"},"content":{"rendered":"\n\t
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Disease description<\/h2>\n\n\n\n

Nephroblastoma, also known as Wilms tumor, is a rare, highly malignant embryonal kidney tumor that predominantly occurs in children, most commonly between the ages of 2 and 5. This type of cancer is named after the German surgeon Max Wilms, who first described the disease in the early 20th century. Nephroblastoma accounts for approximately 5-7% of all pediatric malignancies. Despite its aggressive nature, it generally responds well to treatment, especially when diagnosed at an early stage.<\/p>\n\n\n\n

Nephroblastoma primarily affects the kidneys \u2014 vital organs responsible for blood filtration and excretion of metabolic waste. The tumor can develop in one or both kidneys, although in most cases only one kidney is involved. Depending on the stage of the disease, the tumor may metastasize, that is, spread to other organs such as the lungs, liver, and lymph nodes.<\/p>\n\n\n\n

Wilms tumor typically has a favorable prognosis, especially if the malignancy has not spread beyond the kidney. Remission is achieved in approximately 90% of pediatric patients<\/p>\n\n\n\n

Symptoms<\/h2>\n\n\n\n

The tumor usually does not cause pain, and as a result, it often reaches a significant size by the time it is diagnosed. Most commonly, nephroblastoma is detected due to abdominal enlargement or the discovery of a painless, firm mass during palpation of the abdomen. In approximately 25% of cases, the diagnosis is made based on the presence of gross hematuria \u2014 visible blood in the urine.<\/p>\n\n\n\n

Some symptoms may mimic gastrointestinal disorders and include abdominal pain, nausea, loss of appetite, and constipation. Fever, elevated blood pressure, and general malaise may also be observed. In rare cases, the tumor is identified due to the onset of pain.<\/p>\n\n\n\n

Nephroblastoma is frequently diagnosed before metastases have developed, even when the primary tumor has reached a large size. This contributes to a relatively favorable prognosis, even in the presence of an aggressive (anaplastic) histologic subtype.<\/p>\n\n\n\t\t<\/div>\n\t<\/div>\n\n\n\n\t

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