{"id":5601,"date":"2024-09-22T16:37:10","date_gmt":"2024-09-22T13:37:10","guid":{"rendered":"https:\/\/hospitalitymedservice.com\/?post_type=diseases&p=5601"},"modified":"2025-08-08T10:46:10","modified_gmt":"2025-08-08T07:46:10","slug":"osteosarcoma","status":"publish","type":"diseases","link":"https:\/\/hospitalitymedservice.com\/en\/diseases\/osteosarcoma\/","title":{"rendered":"Osteosarcoma"},"content":{"rendered":"\n\t
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Disease description<\/h2>\n\n\n\n

Osteosarcoma, also known as osteogenic sarcoma, is an aggressive malignant tumor that originates from bone-forming cells. It is the most common primary malignant bone tumor.<\/p>\n\n\n\n

Osteosarcoma most frequently affects the long tubular bones of the upper and lower limbs. The most typical site of origin is the area around the knee joint. However, the disease can also develop in other bones such as the humerus, pelvic bones, ulna, fibula, and cranial bones. The metaphysis \u2014 a part of the bone responsible for growth in children and located between the diaphysis (the shaft of the bone) and the epiphysis (the enlarged end of the bone) \u2014 is particularly prone to involvement.<\/p>\n\n\n\n

The tumor can extend beyond the bone, infiltrating surrounding soft tissues such as muscle, adipose tissue, and tendons. Additionally, malignant cells can spread through the bloodstream and form metastases in distant organs, most commonly the lungs. In some cases, metastases may occur in other organs, including the brain or other skeletal bones.<\/p>\n\n\n\n

Osteosarcoma predominantly affects young individuals during periods of active bone growth and is more commonly diagnosed in male patients. People diagnosed with retinoblastoma (a malignant tumor of the retina) are also at higher risk.<\/p>\n\n\n\n

Symptoms<\/h2>\n\n\n\n

Unfortunately, in the early stages, the disease is often misdiagnosed. Incorrect diagnoses such as myositis, neuralgia, or post-traumatic conditions may delay accurate diagnosis and the initiation of appropriate treatment, which adversely affects prognosis. Therefore, in cases of persistent, unexplained bone pain, it is crucial to consult an oncologist to rule out a tumor.<\/p>\n\n\n\n

The most common symptom is pain near a joint, which intensifies at night or during physical activity. For example, if the leg bones are affected, it may result in limping. In early stages, this pain is often mistaken for muscle strain or trauma. However, unlike those conditions, the pain associated with osteosarcoma does not subside over time but rather worsens.<\/p>\n\n\n\n

As the tumor progresses, additional symptoms develop. Swelling may appear in the affected bone region and increase over time. The skin over the tumor may become edematous, and dilated venous networks may become visible. The pain becomes more intense, limiting the range of motion in the adjacent joint. In some cases, pathological fractures may occur, although this is relatively uncommon.<\/p>\n\n\n\t\t<\/div>\n\t<\/section>\n\n\n\n\t

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