Германия Doctor Robert Thimme

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Doctor's speciality:
Gastroenterologist, Hepatologist, Oncologist

About the doctor

clinical experience
30 years+
scientific publications
100+
scientific awards
7+
provides videoconsultations
📸
The medical director of the therapeutic department
Expert in viral hepatitis
Develops immune restoration models

Dr. Robert Thimme is the medical director of the therapeutic department specializing in gastroenterology, hepatology, endocrinology, and infectious diseases at the University Hospital Freiburg. His department provides care for patients with gastrointestinal tumors, viral hepatitis, and hepatocellular carcinoma. His professional and scientific interests include studying immune responses in hepatitis B (HBV) and hepatitis C (HCV) infections. His research group presented new insights into the mechanisms of T-cell function in viral hepatitis and hepatocellular carcinoma: HLA-B27 antibodies provide protection in HCV infection, but viral escape is the main cause of T-cell failure in chronic HCV infection. Therefore, the development of new cell culture models of virus-specific CD8+ T cells could lead to partial immune restoration.

Since 2021, Dr. Robert Thimme has been a speaker for the BMBF Advanced Clinician Scientist Program: IMMediate — Immune-mediated Diseases, and since 2020, he has been a project leader for H2020 IP-cure B — Interventions for the Cure of Hepatitis B Infection (EU Project).

Key areas of expertise: hepatology and immunology of viral hepatitis.

Main professional interests of Prof. Robert Thimme:

  • Gastroenterology
  • Hepatology
  • Liver diseases
  • Viral hepatitis B and C
  • Liver cancer
  • Liver cirrhosis
  • Portal hypertension
  • Immune response to viral infections
  • Immunology of liver cancer
  • T-cell immunity
  • Immunotherapy
  • Development of new treatments for hepatitis B
  • Immune response to COVID-19
  • Mechanisms of chronic viral infections
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Education

1989-1996 – Faculty of Medicine, Universities of Berlin and Freiburg
1998-2001 – Research associate in the Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, USA (Prof. Dr. F.V. Chisari)
2001-2005 – Specialized training in gastroenterology at the 2nd Department of Internal Medicineicine, University of Freiburg, mentor: Prof. Dr. H.E. Blum — University of Freiburg
2006 — Habilitation in internal medicine, University of Freiburg, mentor: Prof. Dr. H.E. Blum — University of Freiburg

Work Experience

1996-1998 – Physician, 2nd Department of Internal Medicine, University of Freiburg
2005-2009 – Junior Professor, Department of Viral Hepatitis, University of Freiburg
2007-2013 – Senior Registrar, Department of Internal Medicine, University of Freiburg
2009-2013 – Head of the Gerok-Liver Centre, Freiburg
2012-2013 – Assistant Medical Director, Department of Internal Medicine
Since October 2013 — Medical Director, Department of Internal Medicine, University Hospital Freiburg

Professional memberships

Member of the German National Academy of Sciences Leopoldina since 2020
Member of the American Society for Clinical Investigation (ASCI) since 2019
Member of the Advisory Board of the German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) since 2018
Member of the Program Committee of the German Association for the Study of the Liver (GASL) from 2007 to 2009; Scientific Secretary from 2009 to 2012
Member of the Standing Senate Commission on Fundamental Issues in Clinical Research of the German Research Foundation (DFG)
Member of the Scientific Advisory Board of the German Medical Association (Bundesärztekammer) since late 2025, with responsibility for internal medicine, gastroenterology, and transplant medicine

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